Clarithromycin prevents preterm birth and neonatal mortality by dampening alarmin-induced maternal-fetal inflammation in mice

• Prif Awduron: Jose Galaz (Awdur), Roberto Romero (Awdur), Marcia Arenas-Hernandez (Awdur), Marcelo Farias-Jofre (Awdur), Kenichiro Motomura (Awdur), Zhenjie Liu (Awdur), Naoki Kawahara (Awdur), Catherine Demery-Poulos (Awdur), Tzu Ning Liu (Awdur), Justin Padron (Awdur), Bogdan Panaitescu (Awdur), Nardhy Gomez-Lopez (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: BMC, 2022-06-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Abstract Background One of every four preterm neonates is born to a woman with sterile intra-amniotic inflammation (inflammatory process induced by alarmins); yet, this clinical condition still lacks treatment. Herein, we utilized an established murine model of sterile intra-amniotic inflammation in...