18F-FDG PET/CT for Monitoring the Response of Breast Cancer to miR-143-Based Therapeutics by Targeting Tumor Glycolysis

• Autori principali: Ying Miao (Autore), Ling-fei Zhang (Autore), Rui Guo (Autore), Sheng Liang (Autore), Min Zhang (Autore), Shuo Shi (Autore), Cheng-fang (Autore), Mo-fang Liu (Autore), Biao Li (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2016-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Increased glucose utilization is a hallmark of cancer, and tumor metabolism is emerging as anticancer target for therapeutic intervention. Triple-negative breast cancers TNBC are highly glycolytic and show poor clinical outcomes. We previously identified hexokinase 2, the major glycolytic enzyme, as...