RNA Aptamers Rescue Mitochondrial Dysfunction in a Yeast Model of Huntington's Disease
Huntington's disease (HD) is associated with the misfolding and aggregation of mutant huntingtin harboring an elongated polyglutamine stretch at its N terminus. A distinguishing pathological hallmark of HD is mitochondrial dysfunction. Any strategy that can restore the integrity of the mitochon...
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Elsevier,
2018-09-01T00:00:00Z.
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