Population PBPK modeling using parametric and nonparametric methods of the Simcyp Simulator, and Bayesian samplers
Abstract Physiologically‐based pharmacokinetic (PBPK) models usually include a large number of parameters whose values are obtained using in vitro to in vivo extrapolation. However, such extrapolations can be uncertain and may benefit from inclusion of evidence from clinical observations via paramet...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
| Published: |
Wiley,
2022-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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