In Vitro Immune Organs-on-Chip for Drug Development: A Review

• Autori principali: Aya Shanti (Autore), Jeremy Teo (Autore), Cesare Stefanini (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2018-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The current drug development practice lacks reliable and sensitive techniques to evaluate the immunotoxicity of drug candidates, i.e., their effect on the human immune system. This, in part, has resulted in a high attrition rate for novel drugs candidates. Organ-on-chip devices have emerged as key t...