Protein-Mediated Carotenoid Delivery Suppresses the Photoinducible Oxidation of Lipofuscin in Retinal Pigment Epithelial Cells

• Váldodahkkit: Alexey N. Semenov (Dahkki), Eugene G. Maksimov (Dahkki), Anastasia M. Moysenovich (Dahkki), Marina A. Yakovleva (Dahkki), Georgy V. Tsoraev (Dahkki), Alla A. Ramonova (Dahkki), Evgeny A. Shirshin (Dahkki), Nikolai N. Sluchanko (Dahkki), Tatiana B. Feldman (Dahkki), Andrew B. Rubin (Dahkki), Mikhail P. Kirpichnikov (Dahkki), Mikhail A. Ostrovsky (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2023-02-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Lipofuscin of retinal pigment epithelium (RPE) cells is a complex heterogeneous system of chromophores which accumulates as granules during the cell's lifespan. Lipofuscin serves as a source of various cytotoxic effects linked with oxidative stress. Several age-related eye diseases such as macu...