The antiestrogen ICI 182,780 induces early effects on the adult male mouse reproductive tract and long-term decreased fertility without testicular atrophy

• Main Authors: Zhou Qing (Author), Carnes Kay (Author), Nie Rong (Author), Cho Hyun (Author), Sharief Noaman AQ (Author), Hess Rex A (Author)
• Format: Book
• Published: BMC, 2003-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Estrogen receptors (ER) have important physiological roles in both the female and male reproductive systems. Previous studies using the estrogen receptor-α knockout mouse (αERKO) or antiestrogen treatment in adult rodents have shown...