Chuanxiong improves angiogenesis via the PI3K/AKT/Ras/MAPK pathway based on network pharmacology and DESI-MSI metabolomics

• Main Authors: Xue-hao Cheng (Author), Xue-xin Yang (Author), He-rong Cui (Author), Bei-bei Zhang (Author), Ke-dian Chen (Author), Xiao-yun Yang (Author), Jing-yi Jiao (Author), Ya-wen Du (Author), Qi Zhang (Author), Jia-xin Zheng (Author), Wei Xie (Author), Fei-fei Li (Author), Hai-min Lei (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Chuanxiong, a traditional Chinese medicine, has been proved to treat a variety of cardiovascular and cerebrovascular diseases by promoting angiogenesis. However, the mechanisms of Chuanxiong's pro-angiogenesis is currently unknown. This study aimed to uncover the effect and mechan...