12-Deoxyphorbol-13-Hexadecanoate Abrogates OVX-Induced Bone Loss in Mice and Osteoclastogenesis via Inhibiting ROS Level and Regulating RANKL-Mediated NFATc1 Activation

• Prif Awduron: Qi He (Awdur), Junzheng Yang (Awdur), Delong Chen (Awdur), Yejia Li (Awdur), Dawei Gong (Awdur), Hui Ge (Awdur), Zihao Wang (Awdur), Haibin Wang (Awdur), Peng Chen (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Pynciau: article
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Osteoporosis is a major health problem in the elderly. Almost every bone can fracture due to the increased bone fragility in osteoporosis, posing a major challenge to public health. 12-Deoxyphorbol-13-hexadecanoate (DHD), one of the main bioactive components of Stellera chamaejasme L. (Lang Du), is...