A novel cystatin derived from Trichinella spiralis suppresses macrophage-mediated inflammatory responses.

• Main Authors: Porntida Kobpornchai (Author), Robin J Flynn (Author), Onrapak Reamtong (Author), Nonglucksanawan Rittisoonthorn (Author), Nathamon Kosoltanapiwat (Author), Kobporn Boonnak (Author), Usa Boonyuen (Author), Sumate Ampawong (Author), Montakan Jiratanh (Author), Muncharee Tattiyapong (Author), Poom Adisakwattana (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trichinella spiralis can modulate host immune responses to retain a suitable environment for its long-term survival. Incidentally, the parasite elicits regulatory effects through immunomodulatory molecule release, which can suppress host inflammation and may be used for the treatment of unrelated in...