Effects of RANKL Knockdown by Virus-like Particle-Mediated RNAi in a Rat Model of Osteoporosis

Effects of RANKL Knockdown by Virus-like Particle-Mediated RNAi in a Rat Model of Osteoporosis

Rebalancing of the RANKL/OPG system seems to be an effective treatment strategy in postmenopausal osteoporosis. Here, we evaluate the knockdown of RANKL by in-vivo-delivered siRNA in a rat model of osteoporosis. Virus-like-particles (VLPs) derived from polyoma JC virus were used for delivering RANKL...

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Main Authors: Daniel B. Hoffmann (Author), Jens Gruber (Author), Kai O. Böker (Author), Delia Deppe (Author), Stephan Sehmisch (Author), Arndt F. Schilling (Author), Nicolas Lemus-Diaz (Author), Marina Komrakova (Author), Stefan Schneider (Author)
Format: Book
Published: Elsevier, 2018-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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