Cytogenetics and FISH negative cryptic acute promyelocytic leukemia with CD56 expression

• Main Authors: Jhansi Rani Arumugam (Author), B K Karthik Bommannan (Author), Jayachandran Perumal Kalaiyarasi (Author), Shirley Sundersingh (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute promyelocytic leukemia (APL) is characterized by reciprocal translocation t(15;17)(q22;q21) and has a favorable prognosis upon immediate recognition and treatment. However, rare cases of APL show a cryptic insertion of retinoic acid receptor alpha (RARA) gene into promyelocytic leukemia (PML)...