Receptor activator of nuclear factor-κB ligand-mediated osteoclastogenesis signaling pathway and related therapeutic natural compounds

• Main Authors: Zechao Qu (Author), Bo Zhang (Author), Lingbo Kong (Author), Yining Gong (Author), Mingzhe Feng (Author), Xiangcheng Gao (Author), Dong Wang (Author), Liang Yan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoclast is a hematopoietic precursor cell derived from the mononuclear macrophage cell line, which is the only cell with bone resorption function. Its abnormal activation can cause serious osteolysis related diseases such as rheumatoid arthritis, Paget's disease and osteoporosis. In recent y...