High-Resolution Genomic Profiling of Chromosomal Abnormalities in Human Stem Cells Using the 135 K StemArray

Culturing stem cells for an extended period of time can lead to acquired chromosomal aberrations. Determining the copy number variant (CNV) profile of stem cell lines is critical since CNVs can have dramatic effects on gene expression and tumorigenic potential. Here, we describe an improved version...

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Autors principals: Aaron M. Elliott (Autor), Kristi A. Hohenstein Elliott (Autor), Anja Kammesheidt (Autor)
Format: Llibre
Publicat: Hindawi Limited, 2012-01-01T00:00:00Z.
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