Improvement of Targeted Chemotherapy of HER2-positive Ovarian Malignant Cell Line by ZHER2-Idarubicin Conjugate: An in vitro Study

• 主要な著者: Lila Siavoshinia (著者), Mostafa Jamalan (著者), Majid Zeinali (著者), Aminollah Pourshohod (著者), Mahdie Koushki (著者), Bahman Moradipoodeh (著者), Ghorban Mohammadzadeh (著者)
• フォーマット: 図書
• 出版事項: Iranian Society of Pathology, 2020-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background & objectives: Overexpression of human epidermal growth factor receptor 2 (HER2) causes cell transformation and development of various types of malignancies. Idarubicin is an effective anti-neoplastic drug but specific delivery of it to the targeted cells is still a great challenge. Af...