Population pharmacokinetics of voriconazole and initial dosage optimization in patients with talaromycosis

• Main Authors: Zhiwen Jiang (Author), Yinyi Wei (Author), Weie Huang (Author), Bingkun Li (Author), Siru Zhou (Author), Liuwei Liao (Author), Tiantian Li (Author), Tianwei Liang (Author), Xiaoshu Yu (Author), Xiuying Li (Author), Changjing Zhou (Author), Cunwei Cao (Author), TaoTao Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The high variability and unpredictability of the plasma concentration of voriconazole (VRC) pose a major challenge for clinical administration. The aim of this study was to develop a population pharmacokinetics (PPK) model of VRC and identify the factors influencing VRC PPK in patients with talaromy...