Similarities and differences between helminth parasites and cancer cell lines in shaping human monocytes: Insights into parallel mechanisms of immune evasion.

• Main Authors: Prakash Babu Narasimhan (Author), Leor Akabas (Author), Sameha Tariq (Author), Naureen Huda (Author), Sasisekhar Bennuru (Author), Helen Sabzevari (Author), Robert Hofmeister (Author), Thomas B Nutman (Author), Roshanak Tolouei Semnani (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A number of features at the host-parasite interface are reminiscent of those that are also observed at the host-tumor interface. Both cancer cells and parasites establish a tissue microenvironment that allows for immune evasion and may reflect functional alterations of various innate cells. Here, we...