Integrative Ligand-Based Pharmacophore Modeling, Virtual Screening, and Molecular Docking Simulation Approaches Identified Potential Lead Compounds against Pancreatic Cancer by Targeting FAK1

• Автори: Mohammad Habibur Rahman Molla (Автор), Mohammed Othman Aljahdali (Автор), Md Afsar Ahmed Sumon (Автор), Amer H. Asseri (Автор), Hisham N. Altayb (Автор), Md. Shafiqul Islam (Автор), Ahad Amer Alsaiari (Автор), F. A. Dain Md Opo (Автор), Nushrat Jahan (Автор), Foysal Ahammad (Автор), Farhan Mohammad (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2023-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Pancreatic cancer is a very deadly disease with a 5-year survival rate, making it one of the leading causes of cancer-related deaths globally. Focal adhesion kinase 1 (FAK1) is a ubiquitously expressed protein in pancreatic cancer. FAK, a tyrosine kinase that is overexpressed in cancer cells, is cru...