Defining the Effects of PKC Modulator HIV Latency-Reversing Agents on Natural Killer Cells

• Main Authors: Melanie Dimapasoc (Author), Jose Moran (Author), Steve Cole (Author), Alok Ranjan (Author), Rami Hourani (Author), Jocelyn Kim (Author), Paul Wender (Author), Matthew Marsden (Author), Jerome Zack (Author)
• Format: Book
• Published: Case Western Reserve University, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Latency reversing agents (LRAs) such as protein kinase C (PKC) modulators can reduce rebound-competent HIV reservoirs in small animal models. Furthermore, administration of natural killer (NK) cells following LRA treatment improves this reservoir reduction. It is currently unknown why th...