Mixed Pluronic-Cremophor Polymeric Micelles as Nanocarriers for Poorly Soluble Antibiotics-The Influence on the Antibacterial Activity

• Main Authors: Maria Antonia Tănase (Author), Adina Raducan (Author), Petruţa Oancea (Author), Lia Mara Diţu (Author), Miruna Stan (Author), Cristian Petcu (Author), Cristina Scomoroşcenco (Author), Claudia Mihaela Ninciuleanu (Author), Cristina Lavinia Nistor (Author), Ludmila Otilia Cinteza (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this work, novel polymeric mixed micelles from Pluronic F127 and Cremophor EL were investigated as drug delivery systems for Norfloxacin as model antibiotic drug. The optimal molar ratio of surfactants was determined, in order to decrease critical micellar concentration (CMC) and prepare carriers...