QT PRODACT: Sensitivity and Specificity of the Canine Telemetry Assay for Detecting Drug-Induced QT Interval Prolongation

• Main Authors: Hiroyasu Miyazaki (Author), Hiroyuki Watanabe (Author), Tetsuya Kitayama (Author), Masahiro Nishida (Author), Yasuhiro Nishi (Author), Koji Sekiya (Author), Hideki Suganami (Author), Keiji Yamamoto (Author)
• Format: Book
• Published: Elsevier, 2005-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this investigation was to define the sensitivity and specificity of the canine telemetry assay for detecting drug-induced QT interval prolongation. Data from twelve studies generated in the QT PRODACT project were used in this investigation. The study design was a 4 × 4 Latin square c...