Effects of estradiol and progestogens on human breast cells: Regulation of sex steroid receptors

• Main Authors: Fang-Ping Chen (Author), Mei-Hua Chien (Author), Huang-Yang Chen (Author), Ting-Shuo Huang (Author), Yuet-Tong Ng (Author)
• Format: Book
• Published: Elsevier, 2013-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: To examine the effects of 17β-estradiol (E2) and progestogens, used in hormone therapy, on estrogen receptors (ER), progesterone receptors (PR), and human breast tumor cell growth. Materials and methods: MCF-7 cells were incubated in pure E2 (1 nM and 10 nM) as well as in E2 in conjuncti...