Plasma lacosamide monitoring in children with epilepsy: Focus on reference therapeutic range and influencing factors

• Main Authors: Yue Li (Author), Hong-Li Guo (Author), Yuan-Yuan Zhang (Author), Na Dong (Author), Ya-Hui Hu (Author), Jing chen (Author), Xiao-Peng Lu (Author), Feng Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundLacosamide (LCM) is a newer anti-seizure medication (ASM) that was approved in China in 2018, but its real-world clinical data and plasma concentrations in Chinese children with epilepsy are very limited. Of note, the reference range for routine LCM therapeutic drug monitoring is still unk...