Plasma lacosamide monitoring in children with epilepsy: Focus on reference therapeutic range and influencing factors

• Главные авторы: Yue Li (Автор), Hong-Li Guo (Автор), Yuan-Yuan Zhang (Автор), Na Dong (Автор), Ya-Hui Hu (Автор), Jing chen (Автор), Xiao-Peng Lu (Автор), Feng Chen (Автор)
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• Опубликовано: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Предметы: article
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BackgroundLacosamide (LCM) is a newer anti-seizure medication (ASM) that was approved in China in 2018, but its real-world clinical data and plasma concentrations in Chinese children with epilepsy are very limited. Of note, the reference range for routine LCM therapeutic drug monitoring is still unk...