Rosiglitazone increases endothelial cell migration and vascular permeability through Akt phosphorylation

• Main Authors: Yun Hyi Ku (Author), Bong-Jun Cho (Author), Min Joo Kim (Author), Soo Lim (Author), Young Joo Park (Author), Hak C. Jang (Author), Sung Hee Choi (Author)
• Format: Book
• Published: BMC, 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Thiazolidinediones (TZDs), peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists, exhibit anti-inflammatory and antioxidant properties and inhibit endothelial inflammation and dysfunction, which is anti-atherogenic. However, fluid retention, which may lead to congestive...