S-Sulfocysteine Induces Seizure-Like Behaviors in Zebrafish

• Main Authors: Jennifer Plate (Author), Wiebke A. Sassen (Author), Ahmed H. Hassan (Author), Franziska Lehne (Author), Reinhard W. Köster (Author), Tobias Kruse (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2019-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Sulfite is a neurotoxin, which is detoxified by the molybdenum cofactor (Moco)-dependent enzyme sulfite oxidase (SOX). In humans, SOX deficiency causes the formation of the glutamate analog S-Sulfocysteine (SSC) resulting in a constant overstimulation of ionotropic glutamatergic receptors. Overstimu...