Comparative analysis of age in monocrotaline-induced pulmonary hypertensive rats

• Главные авторы: Akiko Kawade (Автор), Aya Yamamura (Автор), Moe Fujiwara (Автор), Saki Kobayashi (Автор), Shiho Mori (Автор), Chihiro Horii (Автор), Akari Hiraku (Автор), Sayo Suzumura (Автор), Kikuo Tsukamoto (Автор), Naoki Ohara (Автор), Rubii Kondo (Автор), Yoshiaki Suzuki (Автор), Hisao Yamamura (Автор)
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• Опубликовано: Elsevier, 2021-09-01T00:00:00Z.
• Предметы: article
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Pulmonary arterial hypertension (PAH) is a rare, progressive, and fatal cardiovascular/lung disease. The incidence rate is affected by age. Monocrotaline (MCT, 60 mg/kg)-treated rats are widely used as an experimental PAH model. Here, we found that young rats died at a mean of 23.4 days after MCT in...