Generation and in vivo characterization of a novel high-affinity human antibody targeting carcinoembryonic antigen

• Main Authors: Louis Plüss (Author), Frederik Peissert (Author), Abdullah Elsayed (Author), Giulia Rotta (Author), Jonas Römer (Author), Sheila Dakhel Plaza (Author), Alessandra Villa (Author), Emanuele Puca (Author), Roberto De Luca (Author), Annette Oxenius (Author), Dario Neri (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTThere are no effective treatment options for most patients with metastatic colorectal cancer (mCRC). mCRC remains a leading cause of tumor-related death, with a five-year survival rate of only 15%, highlighting the urgent need for novel pharmacological products. Current standard drugs are ba...