Relevance of <i>CYP2D6</i> Gene Variants in Population Genetic Differentiation

• Main Authors: Anita Stojanović Marković (Author), Matea Zajc Petranović (Author), Tatjana Škarić-Jurić (Author), Željka Celinšćak (Author), Maja Šetinc (Author), Željka Tomas (Author), Marijana Peričić Salihović (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A significant portion of the variability in complex features, such as drug response, is likely caused by human genetic diversity. One of the highly polymorphic pharmacogenes is <i>CYP2D6</i>, encoding an enzyme involved in the metabolism of about 25% of commonly prescribed drugs. In a di...