Development and Preclinical Evaluation of [⁶⁸Ga]BMSH as a New Potent Positron Emission Tomography Tracer for Imaging Programmed Death-Ligand 1 Expression

• Main Authors: Yong Huang (Author), Chengze Li (Author), Zhongjing Li (Author), Qiong Wang (Author), Size Huang (Author), Qi Liu (Author), Ying Liang (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Immunotherapy targeting the programmed death-ligand 1 (PD-L1)/programmed cell death protein 1 (PD-1) pathway has shown remarkable efficacy against various cancers, but the overall response rate (ORR) is still low. PD-L1 expression in tumors may predict treatment response to immunotherapy. Indeed, on...