Assessing the association between hypoxia during craniofacial development and oral clefts

• Main Authors: Erika Calvano Küchler (Author), Lea Assed da Silva (Author), Paulo Nelson-Filho (Author), Ticiana M. Sabóia (Author), Angela M. Rentschler (Author), José Mauro Granjeiro (Author), Driely Oliveira (Author), Patricia N. Tannure (Author), Raquel Assed da Silva (Author), Leonardo Santos Antunes (Author), Michael Tsang (Author), Alexandre R. Vieira (Author)
• Format: Book
• Published: University of São Paulo, 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objectives To evaluate the association between hypoxia during embryo development and oral clefts in an animal model, and to evaluate the association between polymorphisms in the HIF-1A gene with oral clefts in human families. Material and Methods The study with the animal model used zebrafi...