Decreased Levels of Spleen Tissue CD4+CD25+Foxp3+ Regulatory T Lymphocytes in Mice Exposed to Berberine

• Egile Nagusiak: Gholamreza Karimi (Egilea), Mahmoud Mahmoudi (Egilea), Mahdi Balali-Mood (Egilea), Maryam Rahnama (Egilea), Shahrzad Zamani Taghizadeh Rabe (Egilea), Nafiseh Tabasi (Egilea), Bamdad Riahi-Zanjani (Egilea)
• Formatua: Liburua
• Argitaratua: Medical Association of Pharmacopuncture Institute, 2017-04-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The effects of isoquinoline alkaloid berberine (BER) on spleen tissue CD4+CD25+Foxp3+ regulatory T (Treg) cells were evaluated in BALB/c mice. Here, BER was administered daily by intraperitoneal injection at doses of 5 mg/kg and 10 mg/kg for 14 days. Following the exposure, mice spleen cellularities...