A Single Dose of LSD Does Not Alter Gene Expression of the Serotonin 2A Receptor Gene (HTR2A) or Early Growth Response Genes (EGR1-3) in Healthy Subjects

• Hauptverfasser: Patrick C. Dolder (Verfasst von), Edna Grünblatt (Verfasst von), Felix Müller (Verfasst von), Stefan J. Borgwardt (Verfasst von), Matthias E. Liechti (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• Schlagworte: article
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Rationale: Renewed interest has been seen in the use of lysergic acid diethylamide (LSD) in psychiatric research and practice. The repeated use of LSD leads to tolerance that is believed to result from serotonin (5-HT) 5-HT2A receptor downregulation. In rats, daily LSD administration for 4 days decr...