JAK2 mutation may predict response and guide first line treatment in rheumatoid arthritis

• Main Authors: Yasmin Adel (Author), Mohamed Sabry (Author), Amr Mohamed El-Sabbagh (Author), Yousra Sadeq (Author)
• פורמט: ספר
• יצא לאור: SpringerOpen, 2021-12-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract Background JAK (Janus kinase) inhibitors work by inhibiting the activity of one or more of the enzyme Janus kinase with a therapeutic application for treatment of cancer and inflammatory disorders such as rheumatoid arthritis (RA). We aimed to study impact of JAK2 mutation in serum of rheum...