Vagotomy Affects the Development of Oral Tolerance and Increases Susceptibility to Develop Colitis Independently of α-7 Nicotinic Receptor

• 主要な著者: Martina Di Giovangiulio (著者), Goele Bosmans (著者), Elisa Meroni (著者), Nathalie Stakenborg (著者), Morgane Florens (著者), Giovanna Farro (著者), Pedro J Gomez-Pinilla (著者), Gianluca Matteoli (著者), Guy E Boeckxstaens (著者)
• フォーマット: 図書
• 出版事項: BMC, 2016-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Vagotomy (VGX) increases the susceptibility to develop colitis suggesting a crucial role for the cholinergic anti-inflammatory pathway in the regulation of the immune responses. Since oral tolerance and the generation of regulatory T cells (Tregs) are crucial to preserve mucosal immune home...