Analgesic and anti-inflammatory activities of several 4-substituted-6-(3'-nitrophenyl)pyridazin-(2H)-3-one derivatives

• Hauptverfasser: Anita Singh (Verfasst von), Lakshmayya (Verfasst von), Mohammad Asif (Verfasst von)
• Format: Buch
• Veröffentlicht: Universidade de São Paulo, 2013-12-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Several 6-aryl-4-substituted benzylidene/furfurylidene pyridazin(2H)-3-one derivatives (4a-f) were synthesized and evaluated as analgesic and anti-inflammatory agents in mice and rats, respectively. All compounds were tested by using Eddy's hot plate and the carrageenan-induced hind paw oedema...