Dual-Targeted Self-Assembled DNA Hydrogels Decorated With Multivalent Aptamers Loaded With DOX for Anticancer Therapy

• Main Authors: Fangfang Jin (Author), Qian Zeng (Author), Husun Qian (Author), Dian Zhang (Author), Yu Wei (Author), Yange Wang (Author), Chengsen Chai (Author), Wei Cheng (Author), Shijia Ding (Author), Tingmei Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chemotherapy, as one of the principal modalities for cancer therapy, is limited by its non-specific and inefficient delivery to tumors. To overcome these limitations, we report herein a dual-targeted aptamer-decorated DNA hydrogel system (DTA-H) to achieve efficient, stable, and targeted delivery of...