Anti-malarial artesunate ameliorates atherosclerosis by modulating arterial inflammatory responses via inhibiting the NF-κB-NLRP3 inflammasome pathway

• Main Authors: Yanyan Cen (Author), Yalan Xiong (Author), Rongxin Qin (Author), Hui Tao (Author), Qunfang Yang (Author), Xichun Pan (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Introduction: Chronic inflammation plays a critical role in the pathogenesis of atherosclerosis (AS), and involves a complex interplay between blood components, macrophages, and arterial wall. Therefore, it is valuable in the development of targeted therapies to treat AS.Methods: AS rat model was in...