Pharmacological agents targeting drug-tolerant persister cells in cancer

• المؤلفون الرئيسيون: Yu-Chi Chen (مؤلف), Krishne Gowda (مؤلف), Shantu Amin (مؤلف), Todd D. Schell (مؤلف), Arun K. Sharma (مؤلف), Gavin P. Robertson (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2024-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Current cancer therapy can be effective, but the development of drug resistant disease is the usual outcome. These drugs can eliminate most of the tumor burden but often fail to eliminate the rare, "Drug Tolerant Persister" (DTP) cell subpopulations in residual tumors, which can be referre...