HPLC method development for the simultaneous analysis of amlodipine and valsartan in combined dosage forms and in vitro dissolution studies

• Hoofdauteurs: Mustafa Çelebier (Auteur), Mustafa Sinan Kaynak (Auteur), Sacide Altınöz (Auteur), Selma Sahin (Auteur)
• Formaat: Boek
• Gepubliceerd in: Universidade de São Paulo, 2010-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

A simple, rapid and reproducible HPLC method was developed for the simultaneous determination of amlodipine and valsartan in their combined dosage forms, and for drug dissolution studies. A C18 column (ODS 2, 10 μm, 200 x 4.6 mm) and a mobile phase of phosphate buffer (pH 3.6 , 0.01 mol L-1):acetoni...