Improved Pharmacokinetic Feasibilities of Mirabegron-1,2-Ethanedisulfonic Acid, Mirabegron-1,5-Naphthalenedisulfonic Acid, and Mirabegron-L-Pyroglutamic Acid as Co-Amorphous Dispersions in Rats and Mice

Mirabegron (MBR) is a β<sub>3</sub>-adrenoceptor agonist used for treating overactive bladder syndrome. Due to its poor solubility and low bioavailability (<i>F</i>), the development of novel MBR formulations has garnered increasing attention. Recently, co-amorphous dispersio...

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Main Authors: Seo-Yeon Kim (Author), Byung Hoon You (Author), Mingoo Bae (Author), Seung Yon Han (Author), Kiwon Jung (Author), Young Hee Choi (Author)
Format: Book
Published: MDPI AG, 2023-09-01T00:00:00Z.
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