Unleashing the Potential of Nrf2: A Novel Therapeutic Target for Pulmonary Vascular Remodeling

• Main Authors: Qin Fang (Author), Yang Bai (Author), Shuiqing Hu (Author), Jie Ding (Author), Lei Liu (Author), Meiyan Dai (Author), Jie Qiu (Author), Lujin Wu (Author), Xiaoquan Rao (Author), Yan Wang (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary vascular remodeling, characterized by the thickening of all three layers of the blood vessel wall, plays a central role in the pathogenesis of pulmonary hypertension (PH). Despite the approval of several drugs for PH treatment, their long-term therapeutic effect remains unsatisfactory, as...