Administration of a Histone Deacetylase Inhibitor into the Basolateral Amygdala Enhances Memory Consolidation, Delays Extinction, and Increases Hippocampal BDNF Levels

• Main Authors: Fernanda E. Valiati (Author), Mailton Vasconcelos (Author), Martina Lichtenfels (Author), Fernanda S. Petry (Author), Rosa M. M. de Almeida (Author), Gilberto Schwartsmann (Author), Nadja Schröder (Author), Caroline B. de Farias (Author), Rafael Roesler (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gene expression related to the formation and modification of memories is regulated epigenetically by chromatin remodeling through histone acetylation. Memory formation and extinction can be enhanced by treatment with inhibitors of histone deacetylases (HDACs). The basolateral amygdala (BLA) is a bra...