Modulation of Acid Sphingomyelinase in Melanoma Reprogrammes the Tumour Immune Microenvironment

• প্রধান লেখক: Emma Assi (লেখক), Davide Cervia (লেখক), Laura Bizzozero (লেখক), Annalisa Capobianco (লেখক), Sarah Pambianco (লেখক), Federica Morisi (লেখক), Clara De Palma (লেখক), Claudia Moscheni (লেখক), Paolo Pellegrino (লেখক), Emilio Clementi (লেখক), Cristiana Perrotta (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Hindawi Limited, 2015-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The inflammatory microenvironment induces tumours to acquire an aggressive and immunosuppressive behaviour. Since acid sphingomyelinase (A-SMase) downregulation in melanoma was shown to determine a malignant phenotype, we aimed here to elucidate the role of A-SMase in the regulation of tumour immuno...