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Melatonin suppresses Akt/mTOR/S6K activity, induces cell apoptosis, and synergistically inhibits cell growth with sunitinib in renal carcinoma cells via reversing Warburg effect

ABSTRACTBackground Metabolic alteration drives renal cell carcinoma (RCC) development, while the impact of melatonin (MLT), a neurohormone secreted during darkness, on RCC cell growth and underlying mechanisms remains unclear.Methods We detected concentration of metabolites through metabolomic analy...

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Main Authors:	Kai-Hua Xue (Author), Yi-Fan Jiang (Author), Ji-Yu Bai (Author), Di-Ze Zhang (Author), Yu-Hang Chen (Author), Jian-Bin Ma (Author), Zhi-Jing Zhu (Author), Xinyang Wang (Author), Peng Guo (Author)
Format:	Book
Published:	Taylor & Francis Group, 2023-12-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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