Osteoprotegerin Is more than a Possible Serum Marker in Liver Fibrosis: A Study into Its Function in Human and Murine Liver

• Main Authors: Adhyatmika Adhyatmika (Author), Leonie Beljaars (Author), Kurnia S. S. Putri (Author), Habibie Habibie (Author), Carian E. Boorsma (Author), Catharina Reker-Smit (Author), Theerut Luangmonkong (Author), Burak Guney (Author), Axel Haak (Author), Keri A. Mangnus (Author), Eduard Post (Author), Klaas Poelstra (Author), Kim Ravnskjaer (Author), Peter Olinga (Author), Barbro N. Melgert (Author)
• Format: Book
• Published: MDPI AG, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoprotegerin (OPG) serum levels are associated with liver fibrogenesis and have been proposed as a biomarker for diagnosis. However, the source and role of OPG in liver fibrosis are unknown, as is the question of whether OPG expression responds to treatment. Therefore, we aimed to elucidate the f...