Loganin Exerts Sedative and Hypnotic Effects via Modulation of the Serotonergic System and GABAergic Neurons

• Main Authors: Rui Shi (Author), Yan Han (Author), Yu Yan (Author), Hao-Yi Qiao (Author), Jun He (Author), Wen-Wen Lian (Author), Cong-Yuan Xia (Author), Ting-Li Li (Author), Wei-Ku Zhang (Author), Jie-Kun Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Corni fructus, the fruit of Cornus officinalis Sieb. et Zucc., has been used as a tonic for the kidney in China for thousands of years. Loganin is one of the major constituents derived from Corni fructus. In this study, we revealed the sedative and hypnotic activity of loganin and investigated its m...