Preparation of Chitosan-Plasmid DNA Nanoparticles Encoding Interleukin-12 and their Expression in CT-26 Colon Carcinoma Cells

Preparation of Chitosan-Plasmid DNA Nanoparticles Encoding Interleukin-12 and their Expression in CT-26 Colon Carcinoma Cells

PURPOSE. Interleukin-12 (Il-12) as a cytokine has been proved to possess antitumor effects via stimulating the immune system. Non-viral gene delivery systems exhibit low toxicity and are easier to prepare compared to their viral counterparts. In this study, we aimed to prepare plasmid DNA loaded chi...

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Main Authors: Farzaneh Lotfipour (Author), Somayeh Hallaj-Nezhadi (Author), Hadi Valizadeh (Author), Siavoush Dastmalchi (Author), Behzad Baradaran (Author), Mohammad Barzegar Jalali (Author), Faramarz Dobakhti (Author)
Format: Book
Published: Frontiers Media S.A., 2011-05-01T00:00:00Z.
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