Hypoxia reduces mouse urine output via HIF1α-mediated up-regulation of renal AQP1
Introduction: Patients with acute mountain sickness (AMS) due to hypoxia at high altitudes often exhibit abnormal water metabolism. Hypoxia-inducible factors (HIFs) are major regulators of adaptive responses to hypoxia. As transcription factors, HIFs are involved in the regulation of erythropoiesis,...
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Karger Publishers,
2024-10-01T00:00:00Z.
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