Hypoxia reduces mouse urine output via HIF1α-mediated up-regulation of renal AQP1

• Main Authors: Rongfang Qiao (Author), Xiaohui Cui (Author), Yitong Hu (Author), Haoqing Wei (Author), Hu Xu (Author), Cong Zhang (Author), Chunxiu Du (Author), Jiazhen Chang (Author), Yaqing Li (Author), Wenhua Ming (Author), Yinghui Qi (Author), Youfei Guan (Author), Xiaoyan Zhang (Author)
• Format: Book
• Published: Karger Publishers, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Patients with acute mountain sickness (AMS) due to hypoxia at high altitudes often exhibit abnormal water metabolism. Hypoxia-inducible factors (HIFs) are major regulators of adaptive responses to hypoxia. As transcription factors, HIFs are involved in the regulation of erythropoiesis,...