Topical Wound Treatment with a Nitric Oxide-Releasing PDE5 Inhibitor Formulation Enhances Blood Perfusion and Promotes Healing in Mice

• Main Authors: Maya Ben-Yehuda Greenwald (Author), Yu-Hang Liu (Author), Weiye Li (Author), Paul Hiebert (Author), Maria Zubair (Author), Hermann Tenor (Author), Tobias Braun (Author), Reto Naef (Author), Daniel Razansky (Author), Sabine Werner (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic, non-healing wounds constitute a major health problem, and the current therapeutic options are limited. Therefore, pharmaceuticals that can be locally applied to complicated wounds are urgently needed. Such treatments should directly target the underlying causes, which include diabetes melli...