Hepatitis Delta Virus Detected in Salivary Glands of Sjögren's Syndrome Patients and Recapitulates a Sjögren's Syndrome-Like Phenotype in Vivo

• Main Authors: Melodie L. Weller (Author), Matthew R. Gardener (Author), Zoe C. Bogus (Author), Michael A. Smith (Author), Elisa Astorri (Author), Drew G. Michael (Author), Donald A. Michael (Author), Changyu Zheng (Author), Peter D. Burbelo (Author), Zhennan Lai (Author), Paul A. Wilson (Author), William Swaim (Author), Beverly Handelman (Author), Sandra A. Afione (Author), Michele Bombardieri (Author), John A. Chiorini (Author)
• Format: Book
• Published: Case Western Reserve University, 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Low-level, chronic viral infections have been suspect in the development of select autoimmune diseases, including primary Sjögren's syndrome (pSS). Multiple studies have shown stimulation of antiviral response pathways in pSS tissues suggestive of a viral infection. Yet, with this...